Both sides will be desperate to come away with all three points, after Spurs lost back-to-back matches to fall from the top of the league.
Meanwhile, Wolves followed up their win over Chelsea with a shocking 2-1 defeat at Burnley.
Nuno’s players have been banned from going to supermarkets in order to reduce their risk of contracting coronavirus.
The fixture will kick off at 7:15pm GMT at Molineux Stadium.
The match will be televised on Sky Sports Premier League and Main Event, with coverage from 7pm GMT. Subscribers can also stream the game live on the Sky Sports website and SkyGo app.
Leander Dendoncker is a doubt after suffering an injury against Chelsea, while Raul Jiminez and Jonny remain absent with long-term problems.
Tanguy Ndombele will be available to face Wolves, but fellow midfielder Giovani Lo Celso is out with a hamstring injury sustained against Leicester. Loanee Gareth Bale will be assessed before kick-off after coming off in the League Cup win over Stoke with a calf injury.
Wolves XI: Rui Patricio, Semedo, Coady, Saiss, Marcal, Moutinho, Neves, Traore, Podence, Neto, Fabio Silva
Tottenham XI: Lloris, Doherty, Sanchez, Dier, Davies, Reguilon, Hojbjerg, Winks, Ndombele, Son, Kane.
Tottenham will be desperate for a win, but Wolves are a strong side that impress most against the big sides. With players that can make a difference on either team, I see no separating them at Molineux. 1-1.
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