OXFAM will start reopening charity shops from June 15.
The staggered reopening plan will involve a number of shops in England, with as many as possible by the end of July.
Although, its shops in Scotland and Wales will remain closed at this stage.
Oxfam is still working on the list of shops that will reopen first.
Items will be stored for 72 hours before volunteers can process them, therefore the charity warned that storage space may be limited.
It advised people to call up their local shop to check the best time to donate.
Oxfam is asking volunteers to help with the reopening of its shops.
Each shop typically relies on a team of 30 dedicated volunteers and one or two staff, with more than 20,000 volunteers required in total.
Danny Sriskandarajah, Oxfam GB chief executive, said: “I know that many of us have been busy decluttering under lockdown and we’re really excited about receiving any donations.
“We’re now appealing for volunteers to help us turn these potential treasures into vital funds for life-saving work.”
If you’re interested then you can register your interest online.
Oxfam has 595 shops around the UK.
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Cancer Research UK, which has 600 shops, is planning a phased reopening from June 29.
The Charity Retail Association (CRA) published guidance on what charity shops can do to stop the spread of coronavirus earlier this week.