Alisson will also be required to undertake a late fitness test, with a final training session planned at Melwood on Sunday.
The keeper missed two months of the Premier League last season after suffering a calf injury.
He also struggled with a hip injury in the latter part of the season, missing 14 matches in total last term.
Should he be deemed unavailable, Adrian will likely be the man to take his place.
The Spaniard started in the EFL Cup win over Lincoln City in midweek and could keep hold of that place for the Premier League clash.
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