Martin, who is currently in Edinburgh for new Amazon Prime production The Rig, replied to the Twitter follower after he received anti-Catholic abuse.
Sharing a previous post to Martin about a special Compstonpolitan drink named after him, the Twitter user wrote: “Oh look another puddle drinking t***ier.”
T***ier is a term of sectarian abuse used against Scots of Irish and Catholic origin.
Martin instead joked that the follower, who had also shared a rescue dog post, had misspelled her insult and that she’s meant to write terrier instead.
He told fans: ‘A quick scroll of their timeline shows despite sectarian tendencies she cares passionately about rescue dogs – terriers not t***iers”
Martin’s followers were quick to quip back.
One said: “class response from you as always.”
Someone else said: “Can just see her wee rid coupon pure ragin as she’s typing away.”
Another joked: “I pity the poor dogs that have to live with that.”
It’s not the first time Martin has hit back at trolls.
After someone called him a f***** c*** , he replied: “Here’s the bold @billymanc a man concerned with racism and discrimination.
“Unless you’re a catholic of course. enjoy you’re day billy bhoy.”