A strike from Kai Havertz and a Ben Davies own goal sealed the result in that first fixture within the opening 35 minutes, but Spurs were lucky to escape without further damage in truth.
Spurs have only lost that one game out of their last seven in all competitions as Antonio Conte overseas a gradual improvement, but fringe players have failed to impress, leaving him relying on Harry Kane and Co for the turnaround.
Chelsea have won four and drawn four of their last eight, with just one defeat in all competitions since September.
Here’s everything you need to know ahead of the match.
When is the match?
The game kicks off at 7:45pm GMT on Wednesday 12 January at Tottenham Hotspur Stadium.
Where can I watch it?
The match will be shown live on Sky Sports Main Event, Sky Sports Football and Ultra HD. Subscribers can stream the fixture via the Sky Go app.
If you’re not a Sky customer you can grab a NOWTV Day Pass here to watch without a subscription. We may earn commission from some of the links in this article, but we never allow this to influence our content. This revenue helps to fund journalism across The Independent.
What is the team news?
Spurs will be without centre-backs Eric Dier and the long-term absentee Cristian Romero. Son Heung-min is also facing a spell on the sidelines, while Steven Bergwijn is a doubt and has been widely linked with a move to Ajax this winter.
Chelsea are without goalkeeper Edouard Mendy (Afcon duty), defenders Reece James, Trevoh Chalobah and Ben Chilwell (all injured) and potentially N’Golo Kante and Thiago Silva (both recovering from Covid). Thomas Tuchel has to decide between playing a back three or four in the game after a switch for the first leg.
TOT – Lloris, Tanganga, Sanchez, Davies, Royal, Skipp, Hojbjerg, Reguilon, Lucas, Lo Celso, Kane
CHE – Kepa, Rudiger, Silva, Sarr, Hudson-Odoi, Saul, Kovacic, Alonso, Ziyech, Mount, Lukaku
Spurs might do enough to produce a reaction and get a result on the night, but it’s unlikely they’ll overthrow the champions of Europe entirely. Spurs 1-1 Chelsea (agg 1-3).