The two teams were set to go head to head on January 3, this Sunday.
But the match is now in doubt after a number of cases of Covid-19 at City, which has already interrupted their campaign.
Pep Guardiola’s men were set to face Everton on Monday night but the game was called off due to a spike in positive results in the City camp.
If Chelsea’s match is postponed this weekend, it will leave Lampard with a fixture headache.
But the Englishman admitted that football is secondary when it comes to the pandemic.
“We’ll see what the position is,” said Lampard.
“It’s a key time and a rough time, and we felt that coming with Tier 4 coming in and the surge in Covid.
“From our point of view I will find out more over the next day or two to make sure it has to be safe for the two teams. If not the (City) game won’t go ahead.”
It has been a hectic season so far – so make sure you don’t miss a single thing by signing up for the brilliant new Mirror Football newsletter!
All the latest transfer news and big stories will land straight into your inbox. You won’t miss out.
To sign up, put your email at the top of this article or follow the instructions on this link.
There could be further problems after Chelsea’s next opponents, Morecambe, also saw a surge in cases.
That would mean their FA Cup tie against the Shrimpers, planned for January 10, could also be postponed.
“If we don’t play these games (City and Morecambe) we’ll keep working,” Lampard added.
“I’m not surprised because the way Covid is in the UK is difficult for everybody and football isn’t very different.
“So we’ll just have to see what the Premier League come up with but safety will be paramount.”
Lampard may see this as a blessing in disguise – with the next match scheduled for January 15 against Fulham.
It will give Chelsea an extended break from football at a time where the Blues are creaking in the Premier League.
The latest result saw them draw 1-1 with Aston Villa at Stamford Bridge after Anwar El Ghazi cancelled out Olivier Giroud’s earlier goal.